Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GNRHR | P30968 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232175 | 0.90 | AR (0.38) | SMN1; SMN2GPBAR1KMT2AMEN1LMNA | |
| SCHEMBL6236014 | 0.83 | GNRHR (0.44) | SMN1; SMN2GPBAR1KMT2AMEN1LMNA | |
| SCHEMBL6234217 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2GPBAR1KMT2AMEN1LMNA | |
| SCHEMBL6232179 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2GPBAR1KMT2AMEN1LMNA | |
| SCHEMBL6238955 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2GPBAR1KMT2AMEN1LMNA | |
| SCHEMBL6236017 | 0.70 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AMEN1LMNAPOLB | |
| SCHEMBL6686184 | 0.69 | MAOB (0.50) | LMNA | |
| SCHEMBL6686194 | 0.69 | MAOB (0.50) | LMNA | |
| SCHEMBL6236466 | 0.69 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1LMNAGNRHR | |
| SCHEMBL12642510 | 0.69 | KMT2A (0.48) | SMN1; SMN2KMT2AMEN1LMNAGNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |