Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235662 | 0.91 | ERN1 (0.45) | SMN1; SMN2LMNAALDH1A1TDP1KMT2A | |
| SCHEMBL6235089 | 0.85 | ALDH1A1 (0.50) | SMN1; SMN2LMNAALDH1A1MAPTTDP1 | |
| SCHEMBL6685562 | 0.79 | ALDH1A1 (0.57) | SMN1; SMN2LMNAALDH1A1MAPTTDP1 | |
| SCHEMBL6702861 | 0.78 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL2362378 | 0.76 | MAOA (0.58) | SMN1; SMN2LMNAALDH1A1MAPTTDP1 | |
| SCHEMBL4909005 | 0.76 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL6232024 | 0.75 | AR (0.50) | SMN1; SMN2LMNAALDH1A1MAPTTDP1 | |
| SCHEMBL6236017 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAMAPTTDP1KMT2A | |
| SCHEMBL6686184 | 0.74 | MAOB (0.50) | LMNA | |
| SCHEMBL6254258 | 0.74 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |