Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6234213 | 0.90 | SMN1; SMN2 (0.38) | ARGPBAR1MEN1KMT2ALMNA | |
| SCHEMBL6232179 | 0.79 | SMN1; SMN2 (0.47) | ARGPBAR1MEN1KMT2ALMNA | |
| SCHEMBL6236014 | 0.73 | GNRHR (0.44) | ARGPBAR1MEN1KMT2ALMNA | |
| SCHEMBL6234217 | 0.71 | SMN1; SMN2 (0.49) | GPBAR1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6687664 | 0.71 | MAOB (0.59) | LMNAPARP15PARP10STING1 | |
| SCHEMBL6687667 | 0.71 | MAOB (0.59) | LMNAPARP15PARP10STING1 | |
| SCHEMBL6233698 | 0.70 | SMN1; SMN2 (0.42) | ARGPBAR1MEN1KMT2ALMNA | |
| SCHEMBL6235089 | 0.69 | ALDH1A1 (0.50) | ARGPBAR1MEN1KMT2ALMNA | |
| SCHEMBL6690944 | 0.69 | MAOB (0.48) | LMNAPARP15PARP10STING1TP53 | |
| SCHEMBL6687864 | 0.69 | MAOB (0.45) | MEN1KMT2ALMNASMN1; SMN2PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |