Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561845 | 0.87 | HPSE (0.53) | HPSEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL18493192 | 0.87 | HPSE (0.50) | HPSEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10098857 | 0.84 | ALDH1A1 (0.51) | HPSEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1562841 | 0.84 | HPSE (0.60) | HPSEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5651138 | 0.83 | HPSE (0.50) | HPSEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1562499 | 0.83 | ALDH1A1 (0.54) | HPSEALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL25734944 | 0.83 | HPSE (0.50) | HPSEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL12678273 | 0.83 | HPSE (0.47) | HPSEMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5531874 | 0.81 | ALDH1A1 (0.53) | HPSEKMT2AALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL3072842 | 0.81 | HPSE (0.56) | HPSEMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007634-A1 | 3-HYDROXY-4-OXO-1,2,3-TRIAZINES AND DERIVATIVES THEREOF FOR AMIDE AND ESTER BOND FORMATION | FRUTAROM LTD. (IL) | 2005-01-27 | — | — | WO | disclosed |
| EP-1061904-A1 | NANOPARTICLES, METHOD FOR PRODUCING NANOPARTICLES AND USE OF THE SAME | Aventis Research & Technologies GmbH & Co KG (DE) | 2000-12-27 | — | — | EP | disclosed |
| WO-1999047130-A1 | NANOPARTICLES, METHOD FOR PRODUCING NANOPARTICLES AND USE OF THE SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-09-23 | — | — | WO | disclosed |