Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.77 |
| ▸ | HTR1A | P08908 | 6/20 | 0.77 |
| ▸ | DRD4 | P21917 | 6/20 | 0.77 |
| ▸ | HTR2A | P28223 | 5/20 | 0.77 |
| ▸ | DRD3 | P35462 | 5/20 | 0.77 |
| ▸ | HTR2C | P28335 | 4/20 | 0.77 |
| ▸ | HRH1 | P35367 | 3/20 | 0.77 |
| ▸ | HTR7 | P34969 | 2/20 | 0.73 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.71 |
| ▸ | HTR2B | P41595 | 1/20 | 0.71 |
| ▸ | HTR6 | P50406 | 1/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.71 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11832182 | 0.93 | DRD2 (0.88) | DRD2HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL11828902 | 0.90 | HTR1A (0.68) | DRD2HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL11833639 | 0.87 | DRD2 (0.78) | DRD2HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL8211816 | 0.87 | DRD2 (0.78) | DRD2HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL11828233 | 0.87 | DRD2 (0.77) | DRD2HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL11756285 | 0.86 | HTR1A (0.70) | DRD2HTR1AHTR2AHTR2CHTR7 | |
| SCHEMBL11824823 | 0.86 | HTR1A (0.64) | DRD2HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL11834324 | 0.84 | TSHR (0.67) | DRD2HTR1ADRD4HTR2ADRD3 | |
| SCHEMBL11834858 | 0.84 | TSHR (0.67) | DRD2HTR1ADRD4HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL11829536 | 0.83 | TSHR (0.70) | DRD2HTR1ADRD4HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534239-A2 | PREPARATION OF SUBMICRON SIZED PARTICLES WITH POLYMORPH CONTROL AND NEW POLYMORPH OF ITRACONAZOLE | BAXTER INTERNATIONAL INC. (US) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004054500-A2 | PREPARATION OF SUBMICRON SIZED PARTICLES WITH POLYMORPH CONTROL AND NEW POLYMORPH OF ITRACONAZOLE | BAXTER INTERNATIONAL INC. (US) | 2004-07-01 | — | — | WO | disclosed |
| US-20030096013-A1 | Preparation of submicron sized particles with polymorph control | BAXTER INTERNATIONAL INC. | 2003-05-22 | — | — | US | disclosed |
| US-4065565-A | Acylhydrazones and anti-psychotic compositions thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-12-27 | — | — | US | disclosed |
| US-3933824-A | Piperazinobutyrophenone derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-01-20 | — | — | US | disclosed |