Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14919607 | 0.80 | MAPK1 (0.36) | TSHRLMNATDP1POLBMAPK1 | |
| SCHEMBL6937345 | 0.79 | CA1 (0.55) | TSHRCYP1A2ALPLHSD17B10LMNA | |
| SCHEMBL5739733 | 0.75 | HTR6 (0.48) | TSHRLMNATDP1MAPK1KDM4E | |
| SCHEMBL6941469 | 0.71 | TSHR (0.40) | TSHRCYP1A2ALPLHSD17B10LMNA | |
| SCHEMBL30821607 | 0.70 | ALDH1A1 (0.45) | TSHRCYP1A2ALPLHSD17B10LMNA | |
| SCHEMBL6937363 | 0.70 | ALDH1A1 (0.45) | TSHRCYP1A2ALPLHSD17B10LMNA | |
| SCHEMBL12180600 | 0.69 | SMN1; SMN2 (0.61) | TSHRLMNAPOLBMAPK1FFAR4 | |
| SCHEMBL3631078 | 0.69 | NOTUM (0.55) | TSHRHSD17B10TDP1POLBKDM4E | |
| SCHEMBL22187542 | 0.69 | IDH1 (0.49) | POLBKMT2ACA1CA2CA9 | |
| SCHEMBL29673728 | 0.69 | IDH1 (0.49) | POLBKMT2ACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534654-A1 | METHOD FOR THE SEPARATION OF INTERMEDIATES WHICH MAY BE USED FOR THE PREPARATION OF ESCITALOPRAM | H. LUNDBECK A/S (DK) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004014821-A1 | METHOD FOR THE SEPARATION OF INTERMEDIATES WHICH MAY BE USED FOR THE PREPARATION OF ESCITALOPRAM | H. LUNDBECK A/S (DK) | 2004-02-19 | — | — | WO | disclosed |
| EP-0534667-B1 | Tricyclic heterocycles as PGE2 antagonists | ZENECA LTD (GB) | 1997-02-05 | — | — | EP | disclosed |
| US-5317101-A | Antihyperalgesics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-05-31 | — | — | US | disclosed |
| EP-0534667-A1 | Tricyclic heterocycles as PGE2 antagonists | ZENECA LIMITED (GB) | 1993-03-31 | — | — | EP | disclosed |