Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.55 |
| ▸ | ITGB7 | P26010 | 6/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238356 | 0.92 | BACE1 (0.51) | POLBMAPK1ITGA4ITGB7MMP8 | |
| SCHEMBL13915549 | 0.87 | MMP8 (0.56) | POLBITGA4ITGB7MMP8EGFR | |
| SCHEMBL1931193 | 0.87 | MMP8 (0.56) | POLBITGA4ITGB7MMP8EGFR | |
| SCHEMBL6238689 | 0.86 | PDCD1 (0.44) | POLBMAPK1ITGA4ITGB7EGFR | |
| SCHEMBL6242854 | 0.85 | ITGA4 (0.52) | POLBMAPK1ITGA4ITGB7 | |
| SCHEMBL6234672 | 0.84 | POLB (0.61) | POLBMAPK1ITGA4ITGB7PKM | |
| SCHEMBL6240614 | 0.84 | PPID (0.45) | POLBMAPK1ITGA4ITGB7 | |
| SCHEMBL24925125 | 0.83 | MMP8 (0.57) | POLBMMP8EGFRELANEHPRT1 | |
| SCHEMBL656070 | 0.83 | MMP8 (0.57) | POLBMMP8EGFRELANEHPRT1 | |
| SCHEMBL6237911 | 0.83 | POLB (0.57) | POLBMAPK1ITGA4ITGB7PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955046-B1 | Amino acid derivatives as anti-inflammatory agents | AJINOMOTO KK (JP) | 2005-06-22 | — | — | EP | disclosed |
| US-6552061-B1 | For therapy and prophylaxis of inflammatory skin injuries or diseases | AJINOMOTO CO., INC. (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-0955046-A2 | Amino acid derivatives and anti-inflammatory agents | Ajinomoto Co., Inc. (JP) | 1999-11-10 | — | — | EP | disclosed |