Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.53 |
| ▸ | ITGB7 | P26010 | 6/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243112 | 0.92 | POLB (0.48) | POLBMAPK1ITGA4ITGB7PSMB5 | |
| SCHEMBL6234672 | 0.86 | POLB (0.61) | POLBMAPK1ITGA4ITGB7ALDH1A1 | |
| SCHEMBL6936553 | 0.86 | TLR2 (0.58) | POLBMAPK1ITGA4ITGB7ALDH1A1 | |
| SCHEMBL6936560 | 0.86 | TLR2 (0.58) | POLBMAPK1ITGA4ITGB7ALDH1A1 | |
| SCHEMBL18435163 | 0.83 | CTSS (0.52) | POLBCTSSCTSKBCHEL3MBTL1 | |
| SCHEMBL6234635 | 0.83 | POLB (0.58) | POLBMAPK1ITGA4ITGB7PKM | |
| SCHEMBL28850764 | 0.81 | POLB (0.58) | POLBMAPK1ITGA4ITGB7PKM | |
| SCHEMBL6239432 | 0.79 | POLB (0.49) | POLBMAPK1PKM | |
| SCHEMBL7224165 | 0.79 | GRIA1 (0.53) | — | |
| SCHEMBL22317109 | 0.77 | CTSS (0.52) | POLBCTSSCTSKL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0955046-B1 | Amino acid derivatives as anti-inflammatory agents | AJINOMOTO KK (JP) | 2005-06-22 | — | — | EP | claimed |
| EP-0955046-B1 | Amino acid derivatives as anti-inflammatory agents | AJINOMOTO KK (JP) | 2005-06-22 | — | — | EP | disclosed |
| US-6552061-B1 | For therapy and prophylaxis of inflammatory skin injuries or diseases | AJINOMOTO CO., INC. (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-0955046-A2 | Amino acid derivatives and anti-inflammatory agents | Ajinomoto Co., Inc. (JP) | 1999-11-10 | — | — | EP | disclosed |