SCHEMBL6234772

SCHEMBL6234772

C=C(CC(=O)O)C(=O)OC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALOX15 P16050 1/20 0.40
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35
FFAR3 O14843 1/20 0.33
EGLN1 Q9GZT9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8332200 0.86 HSD17B10 (0.44) HSD17B10TDP1ALOX15ALDH1A1TSHR
SCHEMBL25232 0.85 ALOX15 (0.46) HSD17B10ALOX15ALDH1A1LDHASRR
SCHEMBL27757517 0.84 ALDH1A1 (0.46) HSD17B10TDP1ALOX15ALDH1A1TSHR
SCHEMBL27462226 0.83 ALOX15 (0.44) HSD17B10ALOX15ALDH1A1LDHASRR
SCHEMBL11432063 0.82 HSD17B10 (0.44) HSD17B10TDP1ALDH1A1TSHR
SCHEMBL31563653 0.81 ALOX15 (0.43) HSD17B10ALOX15LDHASRRFFAR3
SCHEMBL8677300 0.80 ALOX15 (0.39) HSD17B10ALOX15ALDH1A1TSHRLDHA
Itaconate SCHEMBL4416065 0.79 ALOX15 (0.58) HSD17B10ALOX15TSHRLDHASRR
Glycolic Acid SCHEMBL11856868 0.79 ALOX15 (0.41) HSD17B10ALOX15LDHASRR
SCHEMBL3673160 0.78 TDP1 (0.50) HSD17B10TDP1ALDH1A1TSHRFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101617006-A Aqueous coating resin composition NIPPON CATALYTIC CHEM IND 2009-12-30 CN disclosed
EP-1021469-B1 RELEASE COATING FOR ADHESIVE ARTICLES AND METHOD MINNESOTA MINING & MFG (US) 2005-05-25 EP disclosed
EP-1021469-A1 RELEASE COATING FOR ADHESIVE ARTICLES AND METHOD MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-07-26 EP disclosed
US-5990238-A AN ADDITION POLYMER, E.G POLYVINYL ALCOHOL, MODIFIED BY A ALKYL ISOCYANATE AND A WATER-SOLUBIZING ANHYDRIDE; NEUTRALIZATION; ANIONIC POLYMERS; FILMS; PRESSURE SENSITIVE ADHESIVES; BACKINGS; STORAGE 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-11-23 US disclosed
WO-1999015568-A1 RELEASE COATING FOR ADHESIVE ARTICLES AND METHOD MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-04-01 WO disclosed
US-3997500-A ADDITION POLYMER THE DOW CHEMICAL COMPANY (US) 1976-12-14 US disclosed
US-3955027-A FLUOROCARBON POLYMERS, EXTENDERS THE DOW CHEMICAL COMPANY (US) 1976-05-04 US disclosed