Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233232 | 0.85 | MAOB (0.54) | MAOBTUBB1MAOAERN1NPC1 | |
| SCHEMBL6233787 | 0.83 | PTPRZ1 (0.57) | TUBB1PTPN1ERN1NPC1RAB9A | |
| SCHEMBL1745424 | 0.81 | MAOB (0.53) | MAOBTUBB1MAOAERN1NPC1 | |
| SCHEMBL23673330 | 0.80 | ERN1 (0.49) | PPARGTUBB1PTPN1CYP1A1CYP1B1 | |
| SCHEMBL16096556 | 0.79 | ERN1 (0.43) | MAOBTUBB1MAOAERN1NPC1 | |
| SCHEMBL856842 | 0.77 | ALDH1A1 (0.60) | NPC1RAB9A | |
| SCHEMBL30873519 | 0.76 | PSEN1 (0.53) | MAOBPPARGTUBB1PTPN1RAB9A | |
| SCHEMBL29227198 | 0.76 | PSEN1 (0.53) | MAOBPPARGTUBB1PTPN1RAB9A | |
| SCHEMBL23683165 | 0.75 | PTPN7 (0.44) | PPARGPPARDPPARATUBB1ERN1 | |
| SCHEMBL18164596 | 0.75 | MAOB (0.70) | MAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |