Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745424 | 0.85 | MAOB (0.53) | MAOBMAOATUBB1ERN1NPC1 | |
| SCHEMBL6234931 | 0.85 | MAOB (0.49) | MAOBMAOATUBB1ERN1NPC1 | |
| SCHEMBL31591495 | 0.83 | ALDH1A1 (0.58) | MAOBMAOATUBB1ERN1NPC1 | |
| SCHEMBL6233787 | 0.81 | PTPRZ1 (0.57) | TUBB1ERN1NPC1RAB9ATDP1 | |
| SCHEMBL28356752 | 0.78 | MAOA (0.48) | MAOAERN1NPC1RAB9AALDH1A1 | |
| SCHEMBL6235662 | 0.78 | ERN1 (0.45) | MAOATUBB1ERN1NPC1RAB9A | |
| SCHEMBL15487329 | 0.78 | NPC1 (0.57) | MAOBNPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL16096702 | 0.77 | ERN1 (0.63) | MAOBMAOATUBB1ERN1NPC1 | |
| SCHEMBL16096556 | 0.77 | ERN1 (0.43) | MAOBMAOATUBB1ERN1NPC1 | |
| SCHEMBL19849607 | 0.76 | ALDH1A1 (0.63) | MAOBMAOATUBB1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |