SCHEMBL6235069

SCHEMBL6235069

[CH2]c1ccc(N(C2CC(C)CCC2C(C)C)C2CC(C)CCC2C(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 4/20 0.39
TRPA1 O75762 2/20 0.39
KCNA5 P22460 1/20 0.38
TRPV1 Q8NER1 6/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
EPHX1 P07099 1/20 0.34
HPGD P15428 1/20 0.33
CYP19A1 P11511 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2481928 0.86 TRPM8 (0.40) TRPM8TRPA1KCNA5TRPV1ALDH1A1
SCHEMBL5182007 0.85 TRPM8 (0.39) TRPM8TRPA1KCNA5TRPV1ALDH1A1
SCHEMBL10949151 0.84 KCNA5 (0.49) TRPM8TRPA1KCNA5TRPV1ALDH1A1
SCHEMBL1903958 0.82 KCNA5 (0.39) TRPM8TRPA1KCNA5TRPV1ALDH1A1
SCHEMBL589762 0.82 CYP19A1 (0.45) TRPM8TRPA1KCNA5TRPV1ALDH1A1
SCHEMBL8470258 0.81 KCNA5 (0.38) TRPM8TRPA1KCNA5TRPV1ALDH1A1
SCHEMBL31752406 0.80 TRPM8 (0.46) TRPM8TRPA1KCNA5TRPV1ALDH1A1
SCHEMBL10363050 0.79 KCNA5 (0.42) TRPM8TRPA1KCNA5TRPV1ALDH1A1
SCHEMBL10363049 0.79 KCNA5 (0.42) TRPM8TRPA1KCNA5TRPV1ALDH1A1
SCHEMBL1757998 0.77 KCNA5 (0.33) TRPM8TRPA1KCNA5TRPV1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005002337-A1 DISINFECTANT COMPOSITIONS AND METHODS VIRTUAL DRUG DEVELOPMENT, INC. (US) 2005-01-13 WO disclosed