Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363049 | 0.84 | KCNA5 (0.42) | KCNA5ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL10363050 | 0.84 | KCNA5 (0.42) | KCNA5ALDH1A1TSHRMAPK1HSD17B10 | |
| SCHEMBL2481928 | 0.82 | TRPM8 (0.40) | KCNA5ALDH1A1TRPM8TRPA1TRPV1 | |
| SCHEMBL1903958 | 0.82 | KCNA5 (0.39) | KCNA5ALDH1A1TRPM8TRPA1TRPV1 | |
| SCHEMBL5182007 | 0.81 | TRPM8 (0.39) | KCNA5ALDH1A1TP53MAPK1TRPM8 | |
| SCHEMBL6235069 | 0.81 | TRPM8 (0.39) | KCNA5ALDH1A1TRPM8TRPA1TRPV1 | |
| SCHEMBL10949151 | 0.81 | KCNA5 (0.49) | KCNA5ALDH1A1TRPM8TRPA1TRPV1 | |
| SCHEMBL31752406 | 0.80 | TRPM8 (0.46) | KCNA5ALDH1A1TRPM8TRPA1TRPV1 | |
| SCHEMBL589762 | 0.78 | CYP19A1 (0.45) | KCNA5ALDH1A1TRPM8TRPA1TRPV1 | |
| SCHEMBL10364041 | 0.78 | NPC1 (0.48) | KCNA5ALDH1A1TSHRMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11322698-A | — | — | None | — | — | JP | disclosed |
| JP-H11322698-A | AZAMETHINE AND ITS PRODUCTION | SIEMENS AG | 1999-11-24 | — | — | JP | disclosed |