SCHEMBL6235210

SCHEMBL6235210

Cc1ccc(OSCCCOP(OCCCSOc2ccc(C)cc2)OCCCSOc2ccc(C)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 8/20 0.36
DRD4 P21917 8/20 0.36
DRD3 P35462 7/20 0.36
ACHE P22303 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KCNH2 Q12809 1/20 0.32
GAA P10253 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6235213 0.77 NPC1 (0.44) DRD2DRD4DRD3MAPTHPGD
SCHEMBL2150871 0.69 MITF (0.39) DRD2DRD4DRD3ACHEL3MBTL1
SCHEMBL2150640 0.69 MITF (0.39) DRD2DRD4DRD3ACHEL3MBTL1
SCHEMBL446285 0.67 NR5A1 (0.41) DRD2DRD4DRD3ACHENPC1
SCHEMBL27458647 0.66 NR5A1 (0.43) DRD2DRD4DRD3MAPTNPC1
SCHEMBL10942876 0.66 NR5A1 (0.43) DRD2DRD4DRD3MAPTNPC1
SCHEMBL6461650 0.66 NR5A1 (0.43) DRD2DRD4DRD3MAPTNPC1
SCHEMBL8389043 0.66 NR5A1 (0.43) DRD2DRD4DRD3MAPTNPC1
SCHEMBL2150758 0.63 ACHE (0.38) DRD2DRD4DRD3ACHEMAPT
SCHEMBL2150414 0.63 ACHE (0.38) DRD2DRD4DRD3ACHEMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0492463-B1 Polyolefin resin composition SUMITOMO CHEMICAL CO (JP) 1995-09-27 EP claimed
US-5346944-A Polyolefin resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-13 US claimed
EP-0492463-A2 Polyolefin resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-01 EP claimed
US-4261880-A HAVING IMPROVED WEATHERING PROPERTIES MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1981-04-14 US claimed
EP-0810261-B9 Additive for resins, process for its preparation and olefin resin composition using this additive MIZUSAWA INDUSTRIAL CHEM (JP) 2005-04-13 EP disclosed
EP-0810261-B1 Additive for resins, process for its preparation and olefin resin composition using this additive MIZUSAWA INDUSTRIAL CHEM (JP) 2004-09-29 EP disclosed
EP-0928807-B1 Zinc-containing hydrotalcite particles and polyolefin resin composition containing them KYOWA CHEM IND CO LTD (JP) 2003-06-25 EP disclosed
US-6221472-B1 HEAT AND CORROSION RESISTANCE; DISCOLORATION INHIBITION KYOWA CHEMICAL INDUSTRY CO LTD (JP) 2001-04-24 US disclosed
US-5961943-A BLENDING AGENT FOR RESINS AND COATING MATERIALS MIZUSAWA INDUSTRIAL CHEMICALS, LTD. (JP) 1999-10-05 US disclosed
EP-0928807-A1 Zinc-containing hydrotalcite particles and polyolefin resin composition containing them Kyowa Chemical Industry Co., Ltd. (JP) 1999-07-14 EP disclosed
US-5891235-A RESIN PLUS ALUMINUM SILICATES MIZUSAWA INDUSTRIAL CHEMICALS, LTD. (JP) 1999-04-06 US disclosed
EP-0810261-A1 Additive for resins, process for its preparation and olefin resin composition using this additive MIZUSAWA INDUSTRIAL CHEMICALS, LTD. (JP) 1997-12-03 EP disclosed
EP-0310092-A2 Can carrier composition UNION CARBIDE CORPORATION (US) 1989-04-05 EP disclosed
US-4795767-A POLYETHYLENE BLEND WITH MINERAL FILLER, SECONDARY AMIDE, ANTIOXIDANT AND PHOSPHORUS COMPOUND UNION CARBIDE CORPORATION (US) 1989-01-03 US disclosed
US-4261880-A HAVING IMPROVED WEATHERING PROPERTIES MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1981-04-14 US disclosed