SCHEMBL6235213

SCHEMBL6235213

Cc1ccc(SCCCOP(OCCCSc2ccc(C)cc2)OCCCSc2ccc(C)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
DRD2 P14416 2/20 0.43
DRD4 P21917 2/20 0.43
POLB P06746 1/20 0.43
ALDH1A1 P00352 5/20 0.42
MAPT P10636 1/20 0.42
DRD3 P35462 1/20 0.42
KDM4E B2RXH2 2/20 0.41
HPGD P15428 5/20 0.40
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5172043 0.81 POLB (0.56) NPC1RAB9ADRD2DRD4POLB
SCHEMBL9808095 0.81 NPC1 (0.55) NPC1RAB9ADRD2DRD4POLB
SCHEMBL5169781 0.79 POLB (0.54) NPC1RAB9ADRD2DRD4POLB
SCHEMBL28435021 0.79 POLB (0.54) NPC1RAB9ADRD2DRD4POLB
SCHEMBL6235210 0.77 DRD2 (0.36) NPC1RAB9ADRD2DRD4MAPT
SCHEMBL5168911 0.76 NPC1 (0.65) NPC1RAB9ADRD2DRD4POLB
SCHEMBL22212775 0.76 NPC1 (0.47) NPC1RAB9ADRD2DRD4POLB
SCHEMBL424971 0.75 HPGD (0.56) NPC1RAB9ADRD2DRD4POLB
SCHEMBL7595139 0.74 NPC1 (0.48) NPC1RAB9ADRD2DRD4POLB
SCHEMBL20040862 0.74 NPC1 (0.48) NPC1RAB9ADRD2DRD4POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0492463-B1 Polyolefin resin composition SUMITOMO CHEMICAL CO (JP) 1995-09-27 EP claimed
US-5346944-A Polyolefin resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-13 US claimed
EP-0492463-A2 Polyolefin resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-01 EP claimed
WO-2022085690-A1 RESIN COMPOSITION AND MOLDED BODY FORMED FROM SAME ユニチカ株式会社 2022-04-28 WO disclosed
EP-0810261-B9 Additive for resins, process for its preparation and olefin resin composition using this additive MIZUSAWA INDUSTRIAL CHEM (JP) 2005-04-13 EP disclosed
EP-0810261-B1 Additive for resins, process for its preparation and olefin resin composition using this additive MIZUSAWA INDUSTRIAL CHEM (JP) 2004-09-29 EP disclosed
US-5961943-A BLENDING AGENT FOR RESINS AND COATING MATERIALS MIZUSAWA INDUSTRIAL CHEMICALS, LTD. (JP) 1999-10-05 US disclosed
US-5891235-A RESIN PLUS ALUMINUM SILICATES MIZUSAWA INDUSTRIAL CHEMICALS, LTD. (JP) 1999-04-06 US disclosed
EP-0810261-A1 Additive for resins, process for its preparation and olefin resin composition using this additive MIZUSAWA INDUSTRIAL CHEMICALS, LTD. (JP) 1997-12-03 EP disclosed