Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235016 | 0.85 | GPR119 (0.42) | ACHEPIK3R1PIK3CAPTPN11DDB1 | |
| SCHEMBL6240664 | 0.81 | ALOX5 (0.49) | MAPK1ACHEDDB1CRBNKMT2A | |
| SCHEMBL1409174 | 0.80 | GPR119 (0.49) | ACHEPIK3CAPOLBPTPN11KMT2A | |
| SCHEMBL15879042 | 0.80 | MEN1 (0.50) | ACHEPIK3CAPOLBPTPN11KMT2A | |
| SCHEMBL14387482 | 0.80 | MEN1 (0.50) | ACHEPIK3CAPOLBPTPN11KMT2A | |
| SCHEMBL12455887 | 0.76 | GPR119 (0.45) | ACHEPIK3CAPOLBPTPN11KMT2A | |
| SCHEMBL12390133 | 0.74 | KMT2A (0.46) | MAPK1ACHEKMT2AMEN1MAPT | |
| SCHEMBL909718 | 0.74 | USP2 (0.56) | PIK3R1PIK3CAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10297496 | 0.74 | GPR119 (0.55) | ACHEPIK3CAPTPN11KMT2AMEN1 | |
| SCHEMBL23175116 | 0.73 | MEN1 (0.47) | ACHEPIK3CAPOLBPTPN11DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |