Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236095 | 0.85 | GPR119 (0.44) | ALOX5EPHX1HTTPDE4AMAPK1 | |
| SCHEMBL6236127 | 0.84 | CTSL (0.60) | ALOX5EPHX1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL15879042 | 0.82 | MEN1 (0.50) | HTTSMN1; SMN2NPSR1ALDH1A1MAPT | |
| SCHEMBL1409174 | 0.82 | GPR119 (0.49) | SMN1; SMN2ALDH1A1MAPTGPR119KMT2A | |
| SCHEMBL14387482 | 0.82 | MEN1 (0.50) | HTTSMN1; SMN2NPSR1ALDH1A1MAPT | |
| SCHEMBL6235271 | 0.81 | MAPK1 (0.41) | ALOX5HTTSMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL6235273 | 0.79 | GPR119 (0.42) | ALOX5EPHX1GPR119KMT2AADORA2A | |
| SCHEMBL6272713 | 0.78 | SMN1; SMN2 (0.63) | HTTSMN1; SMN2NPSR1PDE4AMAPK1 | |
| SCHEMBL4246566 | 0.78 | DDB1 (0.53) | ALOX5HTTSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL12390133 | 0.78 | KMT2A (0.46) | MAPK1ALDH1A1MAPTGPR119KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005011703-A1 | 2-CYANO-1,3,5-TRIAZINE-4,6-DIAMINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2005-02-10 | — | — | WO | disclosed |