Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14154008 | 0.80 | IDO1 (0.50) | CYP1A2LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL332100 | 0.79 | GFER (0.42) | CYP1A2IDO1CYP2C19CA2GFER | |
| SCHEMBL31065470 | 0.78 | TAAR1 (0.52) | CYP1A2CYP2C19TDP1CA1CA2 | |
| Hydrochloric Acid SCHEMBL6004138 | 0.78 | IDO1 (0.48) | CYP1A2LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1806848 | 0.76 | CA2 (0.47) | CYP1A2LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1117946 | 0.76 | CA2 (0.52) | CYP1A2LMNACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7257927 | 0.76 | HRH3 (0.59) | HRH3AOC3TAAR1 | |
| Hydrochloric Acid SCHEMBL4294111 | 0.74 | CA2 (0.45) | CYP1A2LMNACYP3A4CYP2D6CYP2C9 | |
| Bromide SCHEMBL20984397 | 0.74 | CA2 (0.45) | CYP1A2LMNACYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL6100064 | 0.74 | CA2 (0.50) | CYP1A2LMNACYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121153-B1 | SITE-SPECIFIC LABELING OF DISULFIDE-CONTAINING TARGETING VECTORS | IMMUNOMEDICS INC (US) | 2005-04-27 | — | — | EP | disclosed |
| US-6576746-B2 | Contacting protein, peptide, or polypeptide having aldehyde or ketone group with thiol-hydrazine diagnostic agent; chelation, conjugation | IMMUNOMEDICS, INC. | 2003-06-10 | — | — | US | disclosed |
| US-20030092198-A1 | SITE-SPECIFIC LABELING OF DISULFIDE-CONTAINING TARGETING VECTORS | IMMUNOMEDICS, INC. | 2003-05-15 | — | — | US | disclosed |
| EP-1121153-A1 | SITE-SPECIFIC LABELING OF DISULFIDE-CONTAINING TARGETING VECTORS | Immunomedics, Inc. (US) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021573-A1 | SITE-SPECIFIC LABELING OF DISULFIDE-CONTAINING TARGETING VECTORS | IMMUNOMEDICS, INC. (US) | 2000-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092198-A1 | SITE-SPECIFIC LABELING OF DISULFIDE-CONTAINING TARGETING VECTORS | P4HB, DNPEP, PDIA6 | CYP1A2 4613/4885LMNA 3602/4885CYP3A4 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.