Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PDE5A | O76074 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016946 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2PDE5ADRD2ALDH1A1BCL6 | |
| SCHEMBL6238830 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2PDE5ADRD2SIGMAR1ALDH1A1 | |
| SCHEMBL5553491 | 0.80 | GALR1 (0.46) | DRD2 | |
| SCHEMBL5549889 | 0.78 | GALR1 (0.45) | SMN1; SMN2ALDH1A1MAPK1CYP2D6MAPT | |
| SCHEMBL4832202 | 0.77 | DRD2 (0.46) | PDE5ADRD2SIGMAR1CRHBPCRHR2 | |
| SCHEMBL6229931 | 0.77 | GALR1 (0.42) | SMN1; SMN2ALDH1A1CYP2D6KDM4EHSD17B10 | |
| SCHEMBL4836400 | 0.76 | PDE5A (0.46) | SMN1; SMN2PDE5ADRD2RECQL | |
| SCHEMBL5550316 | 0.75 | GALR1 (0.43) | SMN1; SMN2DRD2ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL6608904 | 0.75 | GALR1 (0.43) | SMN1; SMN2DRD2ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL6235105 | 0.75 | SMN1; SMN2 (0.34) | SMN1; SMN2PDE5ADRD2DRD4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560817-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004026844-A1 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2004-04-01 | — | — | WO | claimed |