Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 3/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237656 | 0.80 | SLC1A1 (0.47) | SLC1A2SLC1A1SLC1A3CYP1A2CYP2D6 | |
| SCHEMBL4866933 | 0.75 | SLC1A1 (0.53) | SLC1A2SLC1A1SLC1A3CYP1A2CYP2D6 | |
| SCHEMBL6232780 | 0.75 | SLC1A1 (0.49) | SLC1A2SLC1A1SLC1A3CYP1A2CYP2D6 | |
| SCHEMBL4532053 | 0.74 | SLC1A1 (0.51) | SLC1A2SLC1A1SLC1A3CYP1A2CYP2D6 | |
| SCHEMBL4866841 | 0.74 | SLC1A1 (0.51) | SLC1A2SLC1A1SLC1A3CYP1A2CYP2D6 | |
| SCHEMBL6237054 | 0.72 | ALDH1A1 (0.43) | CYP1A2CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL4864213 | 0.71 | CETP (0.38) | CYP1A2CYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL4864220 | 0.71 | CETP (0.38) | CYP1A2CYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL4866262 | 0.71 | EPHX2 (0.40) | CYP1A2CYP2D6CYP2C9CYP2C19MEN1 | |
| SCHEMBL26961850 | 0.68 | SLC1A2 (0.46) | SLC1A2SLC1A1SLC1A3CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005456-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-01-20 | — | — | WO | disclosed |