Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 7/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4866841 | 0.98 | SLC1A1 (0.51) | SLC1A1SLC1A2SLC1A3KMT2AMEN1 | |
| SCHEMBL4532053 | 0.98 | SLC1A1 (0.51) | SLC1A1SLC1A2SLC1A3KMT2AMEN1 | |
| SCHEMBL6232780 | 0.87 | SLC1A1 (0.49) | SLC1A1SLC1A2SLC1A3KMT2AMEN1 | |
| SCHEMBL21046167 | 0.81 | SLC1A3 (0.44) | SLC1A1SLC1A2SLC1A3KMT2AMEN1 | |
| SCHEMBL6204613 | 0.79 | SLC1A3 (0.43) | SLC1A1SLC1A2SLC1A3KMT2AMEN1 | |
| SCHEMBL6237656 | 0.79 | SLC1A1 (0.47) | SLC1A1SLC1A2SLC1A3KMT2AMEN1 | |
| SCHEMBL10718992 | 0.75 | SLC1A3 (0.42) | SLC1A1SLC1A2SLC1A3KMT2AMEN1 | |
| SCHEMBL9485706 | 0.75 | ALPI (0.47) | SLC1A1SLC1A2SLC1A3CYP1A2ALPI | |
| SCHEMBL26961850 | 0.74 | SLC1A2 (0.46) | SLC1A1SLC1A2SLC1A3KMT2AMEN1 | |
| SCHEMBL10418944 | 0.72 | ALDH1A1 (0.45) | ALDH1A1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332485-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORP (US) | 2008-02-19 | — | — | US | disclosed |
| US-20060160802-A1 | Peptide deformylase inhibitors | GLAXO GROUP LIMITED | 2006-07-20 | — | — | US | disclosed |
| WO-2005005456-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160802-A1 | Peptide deformylase inhibitors | PDF, PEPD, DPEP1 | SLC1A1 3802/4885SLC1A2 4306/4885SLC1A3 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.