Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 5/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235897 | 0.80 | SLC1A2 (0.43) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL4866933 | 0.79 | SLC1A1 (0.53) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL6232780 | 0.78 | SLC1A1 (0.49) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL4532053 | 0.78 | SLC1A1 (0.51) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL4866841 | 0.78 | SLC1A1 (0.51) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL6237219 | 0.69 | ALDH1A1 (0.44) | KMT2AALDH1A1HTR2CLMNA | |
| SCHEMBL26961850 | 0.69 | SLC1A2 (0.46) | SLC1A1SLC1A2SLC1A3MEN1CYP1A2 | |
| SCHEMBL4871791 | 0.68 | HTR2C (0.39) | MEN1KMT2AEPHX2ALDH1A1HTR2C | |
| SCHEMBL4866087 | 0.68 | EPHX2 (0.45) | EPHX2ALDH1A1HTR2CFAAHCNR2 | |
| SCHEMBL6237225 | 0.68 | HTR2C (0.39) | MEN1KMT2AEPHX2ALDH1A1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005456-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-01-20 | — | — | WO | disclosed |