Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844644 | 0.83 | ALOX15 (0.61) | ALOX15ADRB2BRD4IDO1TDO2 | |
| SCHEMBL10631169 | 0.82 | ALOX15 (0.59) | ALOX15ADRB2BRD4IDO1TDO2 | |
| SCHEMBL28364146 | 0.80 | ALOX15 (0.57) | ALOX15BRD4POLBCYP1A2NPSR1 | |
| SCHEMBL6239500 | 0.79 | ALOX15 (0.40) | ALOX15ACP3IDO1TDO2LMNA | |
| SCHEMBL5750561 | 0.78 | ACP3 (0.53) | ACP3POLBLMNASMN1; SMN2NPSR1 | |
| Mifobate SCHEMBL635294 | 0.76 | ALOX15 (1.00) | ALOX15ADRB2BRD4IDO1TDO2 | |
| SCHEMBL11142679 | 0.74 | ALOX15 (0.73) | ALOX15BRD4POLBLMNACYP1A2 | |
| SCHEMBL19638012 | 0.71 | ACP3 (0.58) | BRD4ACP3LMNACYP1A2MAPT | |
| SCHEMBL30266268 | 0.71 | ALOX15 (0.65) | ALOX15ADRB2BRD4IDO1TDO2 | |
| SCHEMBL29098748 | 0.69 | ALOX15 (0.63) | ALOX15ADRB2BRD4IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003143-A1 | NOVEL POTASSIUM CHANNEL MODULATORS | POSEIDON PHARMACEUTICALS A/S (DK) | 2005-01-13 | — | — | WO | claimed |
| WO-2005003143-A1 | NOVEL POTASSIUM CHANNEL MODULATORS | POSEIDON PHARMACEUTICALS A/S (DK) | 2005-01-13 | — | — | WO | disclosed |