Mifobate

Mifobate

SCHEMBL635294

COP(=O)(OC)OC(c1ccc(Cl)cc1)P(=O)(OC)OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 1.00
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ADRB2 P07550 1/20 0.34
BRD4 O60885 1/20 0.33
POLB P06746 1/20 0.33
SLC6A4 P31645 1/20 0.33
CYP1A2 P05177 1/20 0.33
AOC3 Q16853 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5927287 0.90 ALOX15 (0.81) ALOX15MEN1KMT2APOLBCYP1A2
SCHEMBL5926986 0.86 ALOX15 (0.75) ALOX15MEN1KMT2APOLBMAPT
SCHEMBL11142679 0.85 ALOX15 (0.73) ALOX15KMT2ABRD4POLBCYP1A2
SCHEMBL5926887 0.83 ALOX15 (0.71) ALOX15MEN1KMT2AAOC3LMNA
SCHEMBL5926876 0.83 ALOX15 (0.71) ALOX15POLBNPSR1L3MBTL1
SCHEMBL5926897 0.82 ALOX15 (0.70) ALOX15MEN1KMT2APOLBLMNA
SCHEMBL5926896 0.81 ALOX15 (0.68) ALOX15MEN1KMT2APOLBSLC6A4
SCHEMBL5926758 0.80 ALOX15 (0.67) ALOX15SMN1; SMN2
SCHEMBL6552275 0.79 ALOX15 (0.66) ALOX15MEN1KMT2AADRB2BRD4
SCHEMBL5926734 0.79 ALOX15 (0.65) ALOX15IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250297321-A1 METHOD FOR DETECTING METABOLIC REPROGRAMING OF CANCER TOWARDS FATTY ACIDS METABOLISM INST NAT SANTE RECH MED (FR) 2025-09-25 US claimed
EP-4469602-A1 METHOD FOR DETECTING METABOLIC REPROGRAMING OF CANCER TOWARDS FATTY ACIDS METABOLISM Université Paris Cité (FR) 2024-12-04 EP claimed
US-20240190824-A1 INHIBITORS OF TREK (TWIK RELATED K+ CHANNELS) CHANNEL FUNCTION ONO PHARMACEUTICAL CO., LTD. (JP) 2024-06-13 US claimed
US-20240182445-A1 MODULATORS OF TREK (TWIK RELATED K+ CHANNELS) CHANNEL FUNCTION ONO PHARMACEUTICAL CO., LTD. (JP) 2024-06-06 US claimed
CN-107902464-B Tension swing rod device 上海智联精工机械有限公司 2024-05-28 CN claimed
US-11845824-B2 Same novel polymer and organic light emitting device comprising the same LG CHEM, LTD. 2023-12-19 US claimed
WO-2023144357-A1 METHOD FOR DETECTING METABOLIC REPROGRAMING OF CANCER TOWARDS FATTY ACIDS METABOLISM UNIVERSITE PARIS CITE (FR) 2023-08-03 WO claimed
EP-4048399-A1 INHIBITORS OF TREK (TWIK RELATED K+ CHANNELS) CHANNEL FUNCTION ONO Pharmaceutical Co., Ltd. (JP) 2022-08-31 EP claimed
EP-4048659-A1 MODULATORS OF TREK (TWIK RELATED K+ CHANNELS) CHANNEL FUNCTION ONO Pharmaceutical Co., Ltd. (JP) 2022-08-31 EP claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060009423-A1 Phosphonate-phosphate and diphosphonate apolipoprotein e modulators NIESOR ERIC JOSEPH 2006-01-12 US claimed
EP-1485106-A2 PHOSPHONATE-PHOSPHATE AND DIPHOSPHONATE APOLIPOPROTEIN E MODULATORS Ilex Products, Inc. (US) 2004-12-15 EP claimed
WO-2003070179-A2 PHOSPHONATE-PHOSPHATE AND DIPHOSPHONATE APOLIPOPROTEIN E MODULATORS ILEX PRODUCTS, INC. (US) 2003-08-28 WO claimed
US-4416877-A Anti-atherosclerotic pharmaceutical compositions containing diphosphonate compounds SYMPHAR S.A. (CH) 1983-11-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060009423-A1 Phosphonate-phosphate and diphosphonate apolipoprotein e modulators APOB, PHOSPHO1, ENPP2 ALOX15 809/4885MEN1 3169/4885KMT2A 4268/4885
US-20240182445-A1 MODULATORS OF TREK (TWIK RELATED K+ CHANNELS) CHANNEL FUNCTION KCNJ11, KCNJ1, KCNJ2 ALOX15 2756/4885MEN1 2848/4885KMT2A 3385/4885
US-20240190824-A1 INHIBITORS OF TREK (TWIK RELATED K+ CHANNELS) CHANNEL FUNCTION KCNJ11, KCNJ1, KCNJ2 ALOX15 3088/4885MEN1 2570/4885KMT2A 3177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.