Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6235926 | 0.79 | ALOX15 (0.61) | ALOX15IDO1TDO2MAPTLMNA | |
| SCHEMBL5750561 | 0.78 | ACP3 (0.53) | ALDH1A1LMNAACP3MEN1KMT2A | |
| SCHEMBL777805 | 0.71 | ACP3 (0.57) | IDO1TDO2ACP3CA12HDAC3 | |
| SCHEMBL6661073 | 0.70 | KDM4E (0.49) | HSD17B10ALDH1A1LMNAACP3MEN1 | |
| SCHEMBL6239506 | 0.68 | ALDH1A1 (0.52) | ALOX15ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL17923949 | 0.67 | UTRN (0.39) | ALDH1A1KDM4ECA12CA1CA2 | |
| SCHEMBL6206390 | 0.67 | AOC3 (0.44) | IDO1TDO2ALDH1A1MAPTHTT | |
| SCHEMBL781248 | 0.67 | UTRN (0.48) | ALDH1A1SMN1; SMN2GAAKDM4E | |
| SCHEMBL6205426 | 0.66 | AOC3 (0.47) | IDO1TDO2ALDH1A1MAPTHTT | |
| SCHEMBL792136 | 0.66 | IDO1 (0.58) | IDO1TDO2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003143-A1 | NOVEL POTASSIUM CHANNEL MODULATORS | POSEIDON PHARMACEUTICALS A/S (DK) | 2005-01-13 | — | — | WO | claimed |
| WO-2005003143-A1 | NOVEL POTASSIUM CHANNEL MODULATORS | POSEIDON PHARMACEUTICALS A/S (DK) | 2005-01-13 | — | — | WO | disclosed |