Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756627 | 0.87 | MAPT (0.50) | MAPTMAPK1KDM4EHSD17B10ALOX15 | |
| SCHEMBL5613025 | 0.83 | CES2 (0.57) | MAPTMAPK1KDM4EHSD17B10ALOX15 | |
| SCHEMBL7974528 | 0.83 | LMNA (0.48) | MAPTMAPK1KDM4EHSD17B10ALOX15 | |
| SCHEMBL5070586 | 0.82 | ALDH1A1 (0.59) | MAPTMAPK1KDM4EHSD17B10ALOX15 | |
| SCHEMBL5511466 | 0.82 | MAPT (0.64) | MAPTMAPK1KDM4EHSD17B10ALOX15 | |
| SCHEMBL23231693 | 0.82 | MAPT (0.47) | MAPTMAPK1KDM4EHSD17B10ALOX15 | |
| SCHEMBL606872 | 0.81 | TDP1 (0.49) | MAPTMAPK1KDM4EHSD17B10LMNA | |
| SCHEMBL10954888 | 0.79 | MAPT (0.48) | MAPTMAPK1KDM4EHSD17B10ALOX15 | |
| SCHEMBL28552046 | 0.78 | AKR1C3 (0.46) | MAPTMAPK1KDM4EHSD17B10ALOX15 | |
| SCHEMBL10588687 | 0.78 | AKR1C3 (0.48) | MAPTMAPK1KDM4EHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532114-A2 | PROCESS FOR PREPARING QUINOLONE ANTIBIOTIC INTERMEDIATES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6803469-B2 | CYCLIZING IN THE PRESENCE OF A SILYLATING AGENT | THE PROCTER & GAMBLE COMPANY | 2004-10-12 | — | — | US | disclosed |
| US-20040063952-A1 | Process for preparing quinolone antibiotic intermediates | WARNER CHILCOTT COMPANY, LLC | 2004-04-01 | — | — | US | disclosed |
| WO-2004013103-A2 | PROCESS FOR PREPARING QUINOLONE ANTIBIOTIC INTERMEDIATES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063952-A1 | Process for preparing quinolone antibiotic intermediates | QPCT, CCNT1, TOP1 | MAPT 4434/4885MAPK1 1045/4885KDM4E 1114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.