Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 3/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 13/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236045 | 1.00 | CTSA (0.43) | CTSACD274PDCD1PTPN1CASR | |
| SCHEMBL6237287 | 0.88 | CTSA (0.42) | CTSACD274PDCD1CASRPPARG | |
| SCHEMBL6253469 | 0.88 | CTSA (0.42) | CTSACD274PDCD1CASRPPARG | |
| SCHEMBL6232677 | 0.84 | CD274 (0.46) | CD274PDCD1 | |
| SCHEMBL6232680 | 0.84 | CD274 (0.46) | CD274PDCD1 | |
| SCHEMBL6236047 | 0.83 | CTSA (0.45) | CTSACD274CASR | |
| SCHEMBL6232101 | 0.82 | CD274 (0.40) | CTSACD274PDCD1 | |
| SCHEMBL6232098 | 0.82 | CD274 (0.40) | CTSACD274PDCD1 | |
| SCHEMBL6233776 | 0.81 | CD274 (0.45) | CD274PDCD1 | |
| SCHEMBL6238945 | 0.79 | BCHE (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |