SCHEMBL6236047

SCHEMBL6236047

COc1cc(OCc2ccc(C(F)(F)F)cc2)cc(OC)c1CNCC(c1ccccc1)c1ncc(C)s1

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CTSA P10619 6/20 0.45
CD274 Q9NZQ7 12/20 0.42
CASR P41180 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6233074 0.83 CD274 (0.50) CTSACD274
SCHEMBL6236045 0.83 CTSA (0.43) CTSACD274CASR
SCHEMBL6236043 0.83 CTSA (0.43) CTSACD274CASR
SCHEMBL6232102 0.81 CTSA (0.44) CTSACD274
SCHEMBL6237287 0.79 CTSA (0.42) CTSACD274CASR
SCHEMBL6253469 0.79 CTSA (0.42) CTSACD274CASR
SCHEMBL6238954 0.78 BCHE (0.60)
SCHEMBL6237290 0.77 TMEM97 (0.36) CTSACD274
SCHEMBL6233776 0.75 CD274 (0.45) CD274
SCHEMBL6233511 0.72 CTSA (0.42) CTSACD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005000309-A2 CHEMICAL COMPOUNDS IONIX PHARMACEUTICALS LIMITED (GB) 2005-01-06 WO disclosed