Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 19/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233511 | 0.90 | CTSA (0.42) | CD274PDCD1KMT2A | |
| SCHEMBL6230535 | 0.88 | CD274 (0.46) | CD274PDCD1MEN1KMT2ATDP1 | |
| SCHEMBL6233373 | 0.86 | CD274 (0.42) | CD274PDCD1 | |
| SCHEMBL6231277 | 0.85 | PTPRZ1 (0.41) | CD274PDCD1 | |
| SCHEMBL6235977 | 0.84 | KMT2A (0.57) | MEN1KMT2ATDP1 | |
| SCHEMBL6231703 | 0.83 | LMNA (0.53) | MEN1KMT2ATDP1 | |
| SCHEMBL6231706 | 0.83 | LMNA (0.53) | MEN1KMT2ATDP1 | |
| SCHEMBL6257115 | 0.82 | CTSA (0.39) | CD274PDCD1 | |
| SCHEMBL6257119 | 0.82 | CTSA (0.39) | CD274PDCD1 | |
| SCHEMBL6237847 | 0.82 | BCHE (0.54) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000309-A2 | CHEMICAL COMPOUNDS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |