Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.42 |
| ▸ | CTSL | P07711 | 7/20 | 0.42 |
| ▸ | CTSS | P25774 | 7/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099276 | 0.86 | CTSK (0.46) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5092872 | 0.85 | CTSK (0.44) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6237797 | 0.84 | CTSL (0.43) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4791152 | 0.83 | CTSK (0.40) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6255819 | 0.82 | CTSK (0.47) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL5098867 | 0.82 | CTSK (0.42) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6236069 | 0.80 | SMN1; SMN2 (0.38) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4766756 | 0.79 | CTSK (0.53) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6404949 | 0.78 | CTSK (0.50) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL7036859 | 0.78 | CTSK (0.47) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005013909-A2 | NOVEL CATHEPSIN K INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-17 | — | — | WO | disclosed |