Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 16/20 | 0.43 |
| ▸ | CTSK | P43235 | 16/20 | 0.43 |
| ▸ | CTSS | P25774 | 15/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4319024 | 0.85 | CTSK (0.45) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL6236079 | 0.84 | CTSK (0.42) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL6256605 | 0.83 | CTSK (0.46) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL4316707 | 0.80 | CTSS (0.40) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL6237786 | 0.80 | CTSL (0.39) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL6258945 | 0.79 | CTSL (0.49) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL4310385 | 0.74 | CTSK (0.69) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL4312951 | 0.74 | CTSK (0.69) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL4323805 | 0.74 | CTSK (0.69) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL4316429 | 0.74 | CTSK (0.69) | CTSLCTSKCTSSCTSVCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005013909-A2 | NOVEL CATHEPSIN K INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-17 | — | — | WO | disclosed |