Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 5/20 | 0.49 |
| ▸ | EGFR | P00533 | 12/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 10/20 | 0.45 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.42 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236027 | 0.88 | EGFR (0.47) | FLT1EGFRERBB2 | |
| SCHEMBL6236342 | 0.80 | EGFR (0.56) | FLT1EGFRERBB2 | |
| SCHEMBL6236344 | 0.80 | EGFR (0.56) | FLT1EGFRERBB2 | |
| SCHEMBL6239860 | 0.74 | EGFR (0.58) | EGFRERBB2 | |
| SCHEMBL6235814 | 0.74 | EGFR (0.49) | EGFR | |
| SCHEMBL6233383 | 0.74 | NTRK1 (0.40) | FLT1EGFRERBB2 | |
| SCHEMBL6269171 | 0.74 | EGFR (0.41) | EGFRERBB2 | |
| SCHEMBL6252739 | 0.73 | EGFR (0.42) | EGFRERBB2 | |
| SCHEMBL6271807 | 0.72 | EGFR (0.39) | EGFRERBB2 | |
| Trifluoroacetic Acid SCHEMBL6234145 | 0.72 | EGFR (0.67) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | claimed |
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |