Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.39 |
| ▸ | S100A10 | P60903 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800083 | 0.85 | HTR6 (0.38) | MAPTPOLBALDH1A1MEN1GAA | |
| SCHEMBL7098810 | 0.82 | DRD4 (0.35) | MAPTPOLBALDH1A1NPC1MEN1 | |
| SCHEMBL6793606 | 0.79 | MAPKAPK2 (0.45) | MAPTPOLBLMNATP53ALDH1A1 | |
| SCHEMBL6805208 | 0.78 | MEN1 (0.40) | MAPTPOLBLMNAKDM4EMEN1 | |
| SCHEMBL6212034 | 0.69 | CYP1A2 (0.41) | MAPTTP53ALDH1A1MEN1GAA | |
| SCHEMBL6799151 | 0.67 | TDP1 (0.39) | MAPTPOLBTP53ALDH1A1HTT | |
| SCHEMBL2998036 | 0.66 | HTT (0.58) | MAPTPOLBLMNATP53ANXA2 | |
| SCHEMBL2009980 | 0.66 | MEN1 (0.72) | POLBLMNAALDH1A1HTTHDAC3 | |
| SCHEMBL6786592 | 0.65 | HTR2C (0.36) | MAPTALDH1A1KDM4E | |
| SCHEMBL6800731 | 0.64 | HTR2C (0.46) | POLBTP53ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | disclosed |