Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098810 | 0.83 | DRD4 (0.35) | MAPKAPK2HTR2CMAPTPOLBALDH1A1 | |
| SCHEMBL6800083 | 0.77 | HTR6 (0.38) | HTR2CMAPTPOLBTHRBALDH1A1 | |
| SCHEMBL6805208 | 0.76 | MEN1 (0.40) | SMN1; SMN2MAPTLMNAPOLB | |
| SCHEMBL7094558 | 0.70 | ALDH1A1 (0.40) | SMN1; SMN2NAMPTATMFPR2LMNA | |
| SCHEMBL6793600 | 0.67 | SMN1; SMN2 (0.43) | MAPKAPK2SMN1; SMN2ATMAKR1B1MAPT | |
| SCHEMBL6786592 | 0.67 | HTR2C (0.36) | HTR2CSIGMAR1MAPTALDH1A1 | |
| SCHEMBL6799151 | 0.65 | TDP1 (0.39) | SMN1; SMN2HTR2CATMMAPTHTT | |
| SCHEMBL6800731 | 0.65 | HTR2C (0.46) | HTR2CNAMPTPOLBTP53ALDH1A1 | |
| SCHEMBL7278994 | 0.65 | SMN1; SMN2 (0.73) | SMN1; SMN2ATMMAPTFPR2LMNA | |
| Hydrochloric Acid SCHEMBL652812 | 0.63 | HTR2C (1.00) | MAPKAPK2HTR2CSIGMAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029887-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029887-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | CATSPER1, CYP19A1, PDE12 | MAPKAPK2 3594/4885SMN1; SMN2 1213/4885HTR2C 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.