Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236536 | 0.85 | MAPT (0.41) | ALDH1A1MAPTPOLBGAAMEN1 | |
| SCHEMBL7098810 | 0.80 | DRD4 (0.35) | HTR6ALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL6805142 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTHTR2CPOLBMEN1 | |
| SCHEMBL6793606 | 0.77 | MAPKAPK2 (0.45) | ALDH1A1MAPTHTR2CPOLBTHRB | |
| SCHEMBL6805208 | 0.77 | MEN1 (0.40) | MAPTPOLBMEN1KMT2AWNT3A | |
| SCHEMBL6800081 | 0.71 | DRD4 (0.39) | ALDH1A1MAPTDRD4POLBGAA | |
| SCHEMBL7094558 | 0.70 | ALDH1A1 (0.40) | HTR6ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL6209953 | 0.70 | WNT3A (0.42) | HTR6ALDH1A1MAPTHTR2AHTR2C | |
| SCHEMBL6799151 | 0.65 | TDP1 (0.39) | HTR6ALDH1A1MAPTHTR2CPOLB | |
| SCHEMBL8276239 | 0.65 | HTR6 (0.55) | HTR6HTR2AHTR2CHTR7CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029887-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029887-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | CATSPER1, CYP19A1, PDE12 | HTR6 1623/4885ALDH1A1 88/4885MAPT 3896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.