Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | C1S | P09871 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721599 | 0.82 | MAPT (0.40) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL3128742 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL5108178 | 0.79 | TAS2R38 (0.30) | TAS2R38HSD17B10 | |
| SCHEMBL55828 | 0.79 | GAA (0.42) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL11465101 | 0.75 | SMN1; SMN2 (0.32) | TP53TSHRHSD17B10KMT2A | |
| SCHEMBL7392342 | 0.74 | PRSS1 (0.43) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL9725165 | 0.74 | SMN1; SMN2 (0.44) | ALDH1A1TP53TSHRRECQLKMT2A | |
| SCHEMBL5482039 | 0.73 | NPC1 (0.32) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL11072074 | 0.72 | SMN1; SMN2 (0.33) | ALDH1A1TP53TSHRHSD17B10RECQL | |
| SCHEMBL6033544 | 0.72 | SMN1; SMN2 (0.38) | ALDH1A1TP53TSHRHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189607-B | Amine-functional polyamides | 建新公司 | 2018-06-15 | — | — | CN | claimed |
| CN-107250189-A | Crosslinking polydiene propylamine copolymer for treating diabetes B | 建新公司 | 2017-10-13 | — | — | CN | claimed |
| CN-106687504-A | Main chain type polyamines | 建新公司 | 2017-05-17 | — | — | CN | claimed |
| CN-105189607-A | Amine-functional polyamides | GENZYME CORP | 2015-12-23 | — | — | CN | claimed |
| CN-105188718-A | Chelants for advanced glycation end product (AGE) precursors | GENZYME CORP | 2015-12-23 | — | — | CN | claimed |
| EP-2568994-A2 | PROTEASE CATALYZED IN SITU END CAPPING OF OLIGOPEPTIDES IN AQUEOUS MEDIA | Polytechnic Institute of New York University (US) | 2013-03-20 | — | — | EP | claimed |
| US-20120282652-A1 | PREPARATION OF PEPTIDE MIXTURES BY PROTEASE CATALYSIS DESIGNED TO PROVIDE USEFUL BIOLOGICAL AND PHYSICAL PROPERTIES | POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) | 2012-11-08 | — | — | US | claimed |
| WO-2012118780-A2 | PREPARATION OF PEPTIDE MIXTURES BY PROTEASE CATALYSIS DESIGNED TO PROVIDE USEFUL BIOLOGICAL AND PHYSICAL PROPERTIES | POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) | 2012-09-07 | — | — | WO | claimed |
| WO-2011143383-A9 | PROTEASE CATALYZED IN SITU END CAPPING OF OLIGOPEPTIDES IN AQUEOUS MEDIA | POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) | 2012-02-16 | — | — | WO | claimed |
| US-20110287479-A1 | PROTEASE CATALYZED IN SITU END CAPPING OF OLIGOPEPTIDES IN AQUEOUS MEDIA | POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) | 2011-11-24 | — | — | US | claimed |
| EP-0736036-A1 | KININOGEN INHIBITORS | FERRING B.V. (NL) | 1996-10-09 | — | — | EP | claimed |
| EP-0728758-A1 | Dioxopyrrolo-pyrrole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1996-08-28 | — | — | EP | claimed |
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | claimed |
| WO-1995007291-A1 | KININOGEN INHIBITORS | FERRING B.V. (NL) | 1995-03-16 | — | — | WO | claimed |
| US-5376655-A | Elastase inhibitor | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-12-27 | — | — | US | claimed |
| EP-0615978-A1 | Peptide derivatives of the boronic acid having protease inhibiting activity, process for their production and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 1994-09-21 | — | — | EP | claimed |
| EP-0222608-B1 | DERIVATIVES OF P-GUANIDINOBENZOIC ACID AND PHARMACEUTICAL AGENTS CONTAINING THEM AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | claimed |
| US-4975464-A | ADMINISTERING DERIVATIVES OF P-GUANIDINOBENZOIC ACID | IMAKI KATSUHIRO (JP) | 1990-12-04 | — | — | US | claimed |
| EP-0384362-A2 | Glycinderivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-08-29 | — | — | EP | claimed |
| EP-0222608-A2 | Derivatives of p-guanidinobenzoic acid and pharmaceutical agents containing them as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-05-20 | — | — | EP | claimed |