SCHEMBL6236678

SCHEMBL6236678

CC1(C)CC(NC(=O)Cc2cccc(C(=O)NC3CC(C)(C)NC(C)(C)C3)c2)CC(C)(C)N1

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.67
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
EZH2 Q15910 5/20 0.60
GLA P06280 1/20 0.58
POLB P06746 1/20 0.56
CYP2C9 P11712 1/20 0.55
RAD52 P43351 1/20 0.52
ATM Q13315 1/20 0.52
HTT P42858 1/20 0.52
GAA P10253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20533814 0.90 HTT (0.59) L3MBTL1MEN1KMT2AEZH2POLB
SCHEMBL8738955 0.89 MEN1 (0.69) L3MBTL1MEN1KMT2AEZH2GLA
SCHEMBL310763 0.87 KMT2A (0.82) L3MBTL1MEN1KMT2AEZH2GLA
SCHEMBL8739377 0.82 EZH2 (0.78) L3MBTL1MEN1KMT2AEZH2GLA
SCHEMBL4611755 0.81 KMT2A (0.72) L3MBTL1MEN1KMT2AEZH2GLA
SCHEMBL27821167 0.81 KMT2A (0.72) L3MBTL1MEN1KMT2AEZH2GLA
SCHEMBL8738583 0.80 EZH2 (0.62) L3MBTL1MEN1KMT2AEZH2GLA
SCHEMBL2908330 0.80 EZH2 (0.89) L3MBTL1MEN1KMT2AEZH2GLA
SCHEMBL8739222 0.80 KMT2A (0.70) L3MBTL1MEN1KMT2AEZH2GLA
SCHEMBL17067333 0.79 L3MBTL1 (0.74) L3MBTL1MEN1KMT2AEZH2GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448691-B1 METHOD FOR THE PRODUCTION OF POLYCONDENSATES CLARIANT GMBH (DE) 2005-11-16 EP disclosed
EP-1440118-B1 BLENDS OF WAXES AND POLYMER ADDITIVES CLARIANT GMBH (DE) 2005-06-01 EP disclosed
EP-1440118-A1 BLENDS OF WAXES AND POLYMER ADDITIVES Clariant GmbH (DE) 2004-07-28 EP disclosed
WO-2003035745-A1 BLENDS OF WAXES AND POLYMER ADDITIVES CLARIANT GMBH (DE) 2003-05-01 WO disclosed