Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13781620 | 0.84 | FDPS (0.49) | FDPSCHRNB2CHRNA4TBXAS1CYP1A2 | |
| SCHEMBL14145050 | 0.79 | FDPS (0.45) | FDPSCHRNB2CHRNA4TBXAS1CYP1A2 | |
| SCHEMBL103883 | 0.79 | FDPS (0.55) | FDPSCHRNB2CHRNA4TBXAS1CYP1A2 | |
| SCHEMBL24334938 | 0.77 | FDPS (0.53) | FDPSCHRNB2CHRNA4TBXAS1CYP1A2 | |
| SCHEMBL9947015 | 0.77 | SIGMAR1 (0.52) | CYP2D6TDP1 | |
| SCHEMBL2096123 | 0.76 | FDPS (0.51) | FDPSCHRNB2CHRNA4TBXAS1CYP1A2 | |
| SCHEMBL14828666 | 0.76 | FDPS (0.56) | FDPSCHRNB2CHRNA4TBXAS1CYP1A2 | |
| SCHEMBL12632304 | 0.76 | FDPS (0.56) | FDPSCHRNB2CHRNA4TBXAS1CYP1A2 | |
| SCHEMBL12894954 | 0.76 | SLC6A2 (0.57) | FDPSCHRNB2CHRNA4TBXAS1CYP1A2 | |
| SCHEMBL29669201 | 0.76 | SLC6A2 (0.57) | FDPSCHRNB2CHRNA4TBXAS1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521528-A1 | MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES | Sumitomo Chemical Company, Limited (JP) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004006677-A1 | MALONONITRILE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-01-22 | — | — | WO | disclosed |