Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | RXRA | P19793 | 15/20 | 0.59 |
| ▸ | RARB | P10826 | 8/20 | 0.59 |
| ▸ | RARG | P13631 | 7/20 | 0.59 |
| ▸ | RARA | P10276 | 4/20 | 0.56 |
| ▸ | RXRB | P28702 | 4/20 | 0.56 |
| ▸ | RXRG | P48443 | 4/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | HNF4A | P41235 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241850 | 0.93 | RXRA (0.55) | CDC25BATMRXRARARBRARG | |
| SCHEMBL6244136 | 0.91 | RXRA (0.62) | CDC25BATMRXRARARBRARG | |
| SCHEMBL6243030 | 0.90 | RXRA (0.55) | CDC25BATMRXRARARBRARG | |
| SCHEMBL6242986 | 0.89 | RXRA (0.50) | CDC25BATMRXRARARBRARG | |
| SCHEMBL6239474 | 0.88 | RXRA (0.50) | CDC25BATMRXRARARBRARG | |
| SCHEMBL6239175 | 0.85 | RXRA (0.67) | CDC25BATMRXRARARBRARG | |
| SCHEMBL6243489 | 0.84 | RXRA (0.48) | CDC25BATMRXRARARBRARG | |
| SCHEMBL29440075 | 0.83 | RXRA (0.68) | CDC25BRXRARARBRARGRARA | |
| SCHEMBL2128581 | 0.83 | RXRA (0.68) | CDC25BRXRARARBRARGRARA | |
| SCHEMBL6243129 | 0.83 | RXRA (0.55) | RXRARARBRARGRARARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005017185-A2 | HEPATOCYTE NUCLEAR FACTOR 4α MODULATOR COMPOUNDS | LIGAND PHARMCEUTICALS INCORPORATED (US) | 2005-02-24 | — | — | WO | claimed |
| WO-2005017185-A2 | HEPATOCYTE NUCLEAR FACTOR 4α MODULATOR COMPOUNDS | LIGAND PHARMCEUTICALS INCORPORATED (US) | 2005-02-24 | — | — | WO | disclosed |