Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.62 |
| ▸ | RARG | P13631 | 7/20 | 0.62 |
| ▸ | RARB | P10826 | 6/20 | 0.62 |
| ▸ | RXRB | P28702 | 5/20 | 0.62 |
| ▸ | RXRG | P48443 | 5/20 | 0.62 |
| ▸ | RARA | P10276 | 4/20 | 0.62 |
| ▸ | CDC25B | P30305 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236924 | 0.91 | CDC25B (0.59) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL6242127 | 0.87 | RXRA (0.52) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL6241850 | 0.87 | RXRA (0.55) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL6243030 | 0.84 | RXRA (0.55) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL6901726 | 0.83 | RXRA (0.69) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL6242986 | 0.83 | RXRA (0.50) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL6239175 | 0.82 | RXRA (0.67) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL6243489 | 0.81 | RXRA (0.48) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL6243783 | 0.81 | HNF4A (0.60) | RXRARARGRARBRXRBRXRG | |
| SCHEMBL2128581 | 0.80 | RXRA (0.68) | RXRARARGRARBRXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005017185-A2 | HEPATOCYTE NUCLEAR FACTOR 4α MODULATOR COMPOUNDS | LIGAND PHARMCEUTICALS INCORPORATED (US) | 2005-02-24 | — | — | WO | disclosed |