Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2601626 | 0.89 | MEN1 (0.50) | KDM4EALDH1A1MEN1KMT2AMIF | |
| SCHEMBL116517 | 0.86 | MEN1 (0.50) | KDM4EALDH1A1MEN1KMT2AMIF | |
| SCHEMBL6239436 | 0.83 | ALDH1A1 (0.50) | KDM4EALDH1A1MEN1KMT2AMIF | |
| SCHEMBL312535 | 0.80 | CES2 (0.47) | KDM4EALDH1A1MEN1KMT2AMIF | |
| SCHEMBL10565488 | 0.77 | MEN1 (0.60) | KDM4EALDH1A1MEN1KMT2APDE4D | |
| SCHEMBL589507 | 0.76 | KMT2A (0.51) | KDM4EALDH1A1MEN1KMT2AMIF | |
| SCHEMBL30181119 | 0.75 | ALDH1A1 (0.54) | KDM4EALDH1A1MEN1KMT2AMIF | |
| SCHEMBL966496 | 0.75 | ALDH1A1 (0.54) | KDM4EALDH1A1MEN1KMT2AMIF | |
| SCHEMBL1555005 | 0.75 | CPS1 (0.50) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL31493199 | 0.75 | CPS1 (0.50) | KDM4EALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532114-A2 | PROCESS FOR PREPARING QUINOLONE ANTIBIOTIC INTERMEDIATES | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6803469-B2 | CYCLIZING IN THE PRESENCE OF A SILYLATING AGENT | THE PROCTER & GAMBLE COMPANY | 2004-10-12 | — | — | US | disclosed |
| US-20040063952-A1 | Process for preparing quinolone antibiotic intermediates | WARNER CHILCOTT COMPANY, LLC | 2004-04-01 | — | — | US | disclosed |
| WO-2004013103-A2 | PROCESS FOR PREPARING QUINOLONE ANTIBIOTIC INTERMEDIATES | THE PROCTER & GAMBLE COMPANY (US) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063952-A1 | Process for preparing quinolone antibiotic intermediates | QPCT, CCNT1, TOP1 | KDM4E 1114/4885ALDH1A1 751/4885MEN1 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.