Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242051 | 0.87 | MLYCD (0.38) | MLYCDL3MBTL1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3863960 | 0.80 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1LMNATP53MEN1 | |
| SCHEMBL547492 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1LMNATP53MEN1 | |
| SCHEMBL547805 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1LMNATP53MEN1 | |
| SCHEMBL23422467 | 0.75 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1LMNATP53GLA | |
| SCHEMBL16858004 | 0.74 | NPSR1 (0.41) | L3MBTL1SMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL9119942 | 0.73 | MAOB (0.51) | — | |
| SCHEMBL3289116 | 0.73 | AR (0.59) | — | |
| SCHEMBL7639218 | 0.73 | NPSR1 (0.40) | L3MBTL1SMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL8597741 | 0.72 | NPSR1 (0.39) | L3MBTL1SMN1; SMN2ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509495-A1 | ANILINO LIVER X-RECEPTOR MODULATORS | Pharmacia Corporation (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099769-A1 | ANILINO LIVER X-RECEPTOR MODULATORS | PHARMACIA CORPORATION (US) | 2003-12-04 | — | — | WO | disclosed |