Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 10/20 | 0.35 |
| ▸ | CTSL | P07711 | 9/20 | 0.35 |
| ▸ | CTSS | P25774 | 5/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | CTSV | O60911 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210152 | 0.88 | CTSK (0.43) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4046844 | 0.84 | HPGD (0.32) | CHRNA7KDM4EHPGDHSD17B10CTSK | |
| SCHEMBL6209902 | 0.84 | CHRNA7 (0.40) | CHRNA7CHRNB2CHRNA4UGCGKDM4E | |
| SCHEMBL6241602 | 0.82 | CTSK (0.45) | CHRNA7CTSKCTSSCTSB | |
| SCHEMBL6211650 | 0.82 | CCR1 (0.46) | CTSK | |
| SCHEMBL4047816 | 0.80 | CTSK (0.33) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6237568 | 0.80 | CTSK (0.46) | CTSKCTSLCTSSCTSV | |
| SCHEMBL4037229 | 0.80 | CTSK (0.45) | CTSKCTSLCTSSCTSV | |
| SCHEMBL4049558 | 0.80 | CTSK (0.36) | CTSK | |
| SCHEMBL4045332 | 0.79 | CTSK (0.43) | CTSKCTSLCTSSCTSVMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |