Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | BMP1 | P13497 | 4/20 | 0.37 |
| ▸ | MMP12 | P39900 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045579 | 0.90 | HPGD (0.32) | CHRNA7KDM4E | |
| SCHEMBL6210507 | 0.89 | CHRNA7 (0.45) | CHRNA7RXFP1BMP1MMP12HTR3A | |
| SCHEMBL6240769 | 0.88 | CTSK (0.43) | — | |
| SCHEMBL6242334 | 0.87 | TAS1R3 (0.46) | CHRNA7MMP2MMP14CHRNB2CHRNA4 | |
| SCHEMBL6237115 | 0.84 | HRH3 (0.38) | CHRNA7CHRNB2CHRNA4UGCGKDM4E | |
| SCHEMBL4050961 | 0.83 | CTSK (0.36) | CHRNA7RXFP1KDM4E | |
| SCHEMBL4044103 | 0.82 | CTSK (0.42) | — | |
| SCHEMBL4046844 | 0.80 | HPGD (0.32) | CHRNA7RXFP1KDM4E | |
| SCHEMBL4045150 | 0.80 | CTSK (0.44) | — | |
| SCHEMBL6274440 | 0.80 | CTSK (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |