Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.30 |
| ▸ | F10 | P00742 | 2/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046540 | 0.93 | CTSK (0.37) | HPGDKDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL4045579 | 0.90 | HPGD (0.32) | HPGDKDM4ECHRNA7SMN1; SMN2ALDH1A1 | |
| SCHEMBL4047816 | 0.90 | CTSK (0.33) | F2F10CTSK | |
| SCHEMBL4045162 | 0.88 | TAS1R3 (0.34) | F2F10CTSK | |
| SCHEMBL4048801 | 0.86 | CTSK (0.39) | HPGDKDM4EALDH1A1RAB9ACTSK | |
| SCHEMBL6237115 | 0.84 | HRH3 (0.38) | HPGDKDM4ECHRNA7HSD17B10CTSK | |
| SCHEMBL4042524 | 0.84 | CHRNA7 (0.37) | HPGDKDM4ECHRNA7ALDH1A1HSD17B10 | |
| SCHEMBL4049558 | 0.84 | CTSK (0.36) | F2F10CTSK | |
| SCHEMBL4046418 | 0.84 | CTSK (0.33) | F2F10CTSK | |
| SCHEMBL4045167 | 0.83 | ALDH1A1 (0.38) | HPGDKDM4ECHRNA7SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |