Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446022 | 1.00 | MTNR1A (0.54) | MTNR1AMTNR1BAKR1C3CYP2C9GAA | |
| SCHEMBL4258260 | 0.85 | MTNR1A (0.44) | MTNR1AMTNR1BAKR1C3CYP2C9GAA | |
| SCHEMBL17556031 | 0.84 | MTNR1A (0.43) | MTNR1AMTNR1BAKR1C3CYP2C9GAA | |
| SCHEMBL15401581 | 0.83 | MTNR1A (0.43) | MTNR1AMTNR1BAKR1C3CYP2C9GAA | |
| SCHEMBL6242020 | 0.83 | TDP1 (0.44) | MTNR1AMTNR1BPKMMAPTAPEX1 | |
| SCHEMBL18628049 | 0.81 | SLC6A4 (0.45) | MTNR1AMTNR1BAKR1C3LTB4RLTB4R2 | |
| SCHEMBL15239094 | 0.81 | MTNR1A (0.41) | MTNR1AMTNR1BAKR1C3CYP2C9GAA | |
| SCHEMBL14718880 | 0.81 | MTNR1A (0.41) | MTNR1AMTNR1BAKR1C3CYP2C9GAA | |
| SCHEMBL19458776 | 0.80 | KDM4E (0.44) | PKMMAPTAPEX1MEN1ALDH1A1 | |
| SCHEMBL691104 | 0.79 | MTNR1A (0.39) | MTNR1AMTNR1BAKR1C3GAALTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390427-B1 | POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE | CONSTR RES & TECH GMBH (DE) | 2005-06-08 | — | — | EP | claimed |
| US-20030119955-A1 | Polymeric structural support membrane | MBT HOLDING AG | 2003-06-26 | — | — | US | claimed |
| EP-1390427-B1 | POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE | CONSTR RES & TECH GMBH (DE) | 2005-06-08 | — | — | EP | disclosed |
| EP-1390427-A2 | POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE | Construction Research & Technology GmbH (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-20030119955-A1 | Polymeric structural support membrane | MBT HOLDING AG | 2003-06-26 | — | — | US | disclosed |
| US-20020151637-A1 | Polymeric structural support membrane | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2002-10-17 | — | — | US | disclosed |
| WO-2002070591-A2 | POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE | MBT HOLDING AG (CH) | 2002-09-12 | — | — | WO | disclosed |