SCHEMBL446022

SCHEMBL446022

CC(=CCC(C)Oc1ccccc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 8/20 0.54
MTNR1B P49286 8/20 0.54
AKR1C3 P42330 1/20 0.41
CYP2C9 P11712 2/20 0.40
GAA P10253 2/20 0.39
CYP1A2 P05177 1/20 0.39
PKM P14618 1/20 0.39
CYP2C19 P33261 1/20 0.39
LTB4R Q15722 2/20 0.39
LTB4R2 Q9NPC1 2/20 0.39
MAPT P10636 1/20 0.38
APEX1 P27695 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6237193 1.00 MTNR1A (0.54) MTNR1AMTNR1BAKR1C3CYP2C9GAA
SCHEMBL4258260 0.85 MTNR1A (0.44) MTNR1AMTNR1BAKR1C3CYP2C9GAA
SCHEMBL17556031 0.84 MTNR1A (0.43) MTNR1AMTNR1BAKR1C3CYP2C9GAA
SCHEMBL15401581 0.83 MTNR1A (0.43) MTNR1AMTNR1BAKR1C3CYP2C9GAA
SCHEMBL6242020 0.83 TDP1 (0.44) MTNR1AMTNR1BPKMMAPTAPEX1
SCHEMBL18628049 0.81 SLC6A4 (0.45) MTNR1AMTNR1BAKR1C3LTB4RLTB4R2
SCHEMBL15239094 0.81 MTNR1A (0.41) MTNR1AMTNR1BAKR1C3CYP2C9GAA
SCHEMBL14718880 0.81 MTNR1A (0.41) MTNR1AMTNR1BAKR1C3CYP2C9GAA
SCHEMBL19458776 0.80 KDM4E (0.44) PKMMAPTAPEX1MEN1ALDH1A1
SCHEMBL691104 0.79 MTNR1A (0.39) MTNR1AMTNR1BAKR1C3GAALTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363467-A1 NOVEL DUAL CURE 3D PRINTING RESINS Stratasys, Inc. (US) 2024-05-08 EP claimed
EP-4363223-A1 NOVEL URETHANE ACRYLATE COMPOSITION Stratasys, Inc. (US) 2024-05-08 EP claimed
US-11891469-B2 Urethane acrylate composition STRATASYS, INC. (US) 2024-02-06 US claimed
WO-2023278202-A1 NOVEL URETHANE ACRYLATE COMPOSITION COVESTRO LLC (US) 2023-01-05 WO claimed
WO-2023278201-A1 NOVEL DUAL CURE 3D PRINTING RESINS COVESTRO LLC (US) 2023-01-05 WO claimed
US-20220411563-A1 NOVEL DUAL CURE 3D PRINTING RESINS STRATASYS INC. 2022-12-29 US claimed
US-20220411560-A1 NOVEL URETHANE ACRYLATE COMPOSITION STRATASYS INC. 2022-12-29 US claimed
EP-1390427-B1 POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE CONSTR RES & TECH GMBH (DE) 2005-06-08 EP claimed
US-20030119955-A1 Polymeric structural support membrane MBT HOLDING AG 2003-06-26 US claimed
WO-2024111521-A1 CURABLE COMPOSITION, FILM FORMING METHOD AND ARTICLE MANUFACTURING METHOD CANON KABUSHIKI KAISHA (JP) 2024-05-30 WO disclosed
US-20240166787-A1 COMPOSITIONS, POLYMERIC FILMS, AND ARTICLES INCLUDING A CHEMICAL BLOWING AGENT AND/OR A CROSSLINKER HAVING A PHOTODEGRADABLE LINKAGE, FOAM COMPOSITIONS, METHODS, AND CROSSLINKERS 3M INNOVATIVE PROPERTIES COMPANY 2024-05-23 US disclosed
EP-4363467-A1 NOVEL DUAL CURE 3D PRINTING RESINS Stratasys, Inc. (US) 2024-05-08 EP disclosed
EP-4363223-A1 NOVEL URETHANE ACRYLATE COMPOSITION Stratasys, Inc. (US) 2024-05-08 EP disclosed
US-11904031-B2 Orthodontic articles comprising polymerized composition comprising at least two free-radical initiators 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-02-20 US disclosed
EP-1382446-A1 Laminate for IR ablation Toyo Boseki Kabushiki Kaisha (JP) 2004-01-21 EP disclosed
US-20030119955-A1 Polymeric structural support membrane MBT HOLDING AG 2003-06-26 US disclosed
EP-1306725-A1 Photosensitive resin laminate Toyo Boseki Kabushiki Kaisha (JP) 2003-05-02 EP disclosed
US-20030082482-A1 Photosensitive resin laminate TOYO BOSEKI KABUSHIKI KAISHA (JP) 2003-05-01 US disclosed
US-20020151637-A1 Polymeric structural support membrane CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2002-10-17 US disclosed
WO-2002070591-A2 POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE MBT HOLDING AG (CH) 2002-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11904031-B2 Orthodontic articles comprising polymerized composition comprising at least two free-radical initiators ELL, PAM, HDAC10 MTNR1A 1068/4885MTNR1B 1323/4885AKR1C3 2112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.