Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29723033 | 0.83 | POLB (0.49) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL446022 | 0.83 | MTNR1A (0.54) | APEX1MTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL6237193 | 0.83 | MTNR1A (0.54) | APEX1MTNR1AMTNR1BRAB9ANPC1 | |
| SCHEMBL6242016 | 0.81 | TDP1 (0.44) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL7184070 | 0.81 | TDP1 (0.51) | TDP1POLBAPEX1HTTTHRB | |
| Methacrylic Acid SCHEMBL17911799 | 0.80 | TDP1 (0.58) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL21371 | 0.80 | TDP1 (0.61) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL15510927 | 0.80 | TSHR (0.44) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL28331865 | 0.79 | TDP1 (0.60) | TDP1POLBAPEX1HTTTHRB | |
| SCHEMBL1224847 | 0.79 | TDP1 (0.44) | TDP1POLBAPEX1HTTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390427-B1 | POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE | CONSTR RES & TECH GMBH (DE) | 2005-06-08 | — | — | EP | claimed |
| EP-1390427-A2 | POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE | Construction Research & Technology GmbH (DE) | 2004-02-25 | — | — | EP | claimed |
| US-20020151637-A1 | Polymeric structural support membrane | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2002-10-17 | — | — | US | claimed |
| WO-2002070591-A2 | POLYMERIC EXCAVATION STRUCTURAL SUPPORT MEMBRANE | MBT HOLDING AG (CH) | 2002-09-12 | — | — | WO | claimed |