Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871791 | 1.00 | HTR2C (0.39) | HTR2CNPC1RAB9ALMNAPPARG | |
| SCHEMBL4871801 | 1.00 | HTR2C (0.39) | HTR2CNPC1RAB9ALMNAPPARG | |
| SCHEMBL6231915 | 0.90 | ADAM17 (0.40) | HTR2CNPC1RAB9ALMNANAMPT | |
| SCHEMBL4869758 | 0.90 | ADAM17 (0.40) | HTR2CNPC1RAB9ALMNANAMPT | |
| SCHEMBL4863343 | 0.86 | ALDH1A1 (0.40) | HTR2CNPC1RAB9ALMNAPPARG | |
| SCHEMBL4863333 | 0.86 | ALDH1A1 (0.40) | HTR2CNPC1RAB9ALMNAPPARG | |
| SCHEMBL4863329 | 0.86 | ALDH1A1 (0.40) | HTR2CNPC1RAB9ALMNAPPARG | |
| SCHEMBL4866100 | 0.86 | ALDH1A1 (0.40) | HTR2CNPC1RAB9ALMNAPPARG | |
| SCHEMBL4863361 | 0.81 | LMNA (0.41) | NPC1RAB9ALMNAPPARGPPARA | |
| SCHEMBL4864213 | 0.80 | CETP (0.38) | HTR2CNPC1RAB9ALMNAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005456-A2 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-01-20 | — | — | WO | disclosed |