Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240509 | 0.81 | HTT (0.41) | MEN1KMT2AALDH1A1ABL1IDO1 | |
| SCHEMBL2093652 | 0.81 | EPHX2 (0.49) | L3MBTL1MEN1KMT2AALDH1A1IDO1 | |
| SCHEMBL1090652 | 0.81 | LMNA (0.47) | L3MBTL1MEN1KMT2AALDH1A1ABL1 | |
| SCHEMBL27684285 | 0.77 | POLB (0.53) | L3MBTL1MEN1KMT2AALDH1A1ABL1 | |
| SCHEMBL1411957 | 0.71 | CFTR (0.44) | L3MBTL1MEN1KMT2AALDH1A1ABL1 | |
| SCHEMBL921646 | 0.69 | ALDH1A1 (0.37) | L3MBTL1MEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL1091848 | 0.69 | KMT2A (0.48) | MEN1KMT2AALDH1A1IDO1NPC1 | |
| SCHEMBL1091660 | 0.68 | IDO1 (0.40) | KMT2AALDH1A1AOC3HSP90AB1IDO1 | |
| SCHEMBL6241817 | 0.67 | RAB9A (0.38) | L3MBTL1MEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL1106684 | 0.67 | IDO1 (0.58) | MEN1KMT2AALDH1A1HSP90AB1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | claimed |
| WO-2015124606-A1 | N-SUBSTITUTED IMINO HETEROCYCLIC COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2015-08-27 | — | — | WO | disclosed |
| WO-2005005382-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-01-20 | — | — | WO | disclosed |